DHEA: What You Need to Know Before You Buy

DHEA is sold over the counter as a supplement, not FDA-approved as a drug. Here's what the evidence says and why your doctor should weigh in.

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What DHEA Is

DHEA (dehydroepiandrosterone) is a hormone your body makes naturally. It's a precursor to testosterone and estrogen, meaning your body converts it into those hormones.

You can buy DHEA over the counter as a dietary supplement. It's not FDA-approved as a medication, which means it hasn't gone through the same testing and approval process drugs do.

Why People Use It

People take DHEA supplements for several reasons:

  • Age-related hormone decline
  • Sexual function and libido
  • Mood and cognitive function
  • Muscle strength and body composition
  • General wellness as you age

What the Evidence Shows

The research on DHEA is mixed. Some studies suggest modest benefits for specific uses, but evidence is weak or inconsistent in most areas. Quality matters: supplement companies aren't required to prove their products work before selling them.

Important Things to Know

Supplement, not drug: DHEA isn't regulated the way medications are. Labels may not reflect what's actually in the bottle or in what dose.

Individual variation: Your body's response depends on your age, sex, baseline hormone levels and overall health.

Interactions matter: DHEA can interact with medications and supplements. Discuss it with your doctor before starting.

Not right for everyone: People with hormone-sensitive conditions like breast cancer or prostate issues should avoid DHEA without medical guidance.

Talk to Your Doctor

If you're considering DHEA, get your baseline hormone levels tested first and discuss it with your healthcare provider. They can advise whether it makes sense for you and monitor you if you use it.

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