hCG (Human Chorionic Gonadotropin): What It Is and How It's Used
hCG is a hormone produced during pregnancy and used in fertility treatments. Learn how it works, why doctors prescribe it, and what to expect from treatment.
What is hCG?
hCG, or human chorionic gonadotropin, is a hormone your body produces naturally during pregnancy. It's also manufactured as a medication for fertility treatment.
How hCG Works
After conception, hCG levels rise rapidly and maintain pregnancy by keeping the corpus luteum active. This gland produces progesterone, which is essential for early pregnancy.
In fertility treatment, injectable hCG mimics this natural hormone to trigger ovulation or support the luteal phase after egg retrieval.
Medical Uses
Doctors prescribe hCG for:
- Triggering final egg maturation before IVF collection
- Supporting the luteal phase in fertility cycles
- Treating certain hormone-related conditions in men and women
- Stimulating testosterone production in males
How It's Administered
hCG comes as an injection, typically given subcutaneously (under the skin) or intramuscularly (into muscle). Timing is critical in fertility treatment, often coordinated precisely with other medications.
Side Effects
Common side effects include injection site reactions, mild headache, and fatigue. More serious but rare complications include ovarian hyperstimulation syndrome (OHSS) when used with other fertility drugs.
Cost Considerations
hCG costs vary significantly based on brand, dosage, and supplier. Fertility medication costs often aren't covered by insurance, making price comparison important before treatment begins.