Insulin lispro: rapid-acting diabetes medication

Insulin lispro is a rapid-acting insulin that works fast to control blood sugar after meals. How it works, what to expect, and what it costs.

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Insulin lispro is a rapid-acting insulin used to manage type 1 and type 2 diabetes. It starts working within 15 minutes of injection and reaches peak effectiveness in 30 to 90 minutes, making it useful for controlling blood sugar spikes after meals.

How it works

Insulin lispro is a genetically engineered form of human insulin. It's absorbed quickly into the bloodstream and binds to insulin receptors on cells, allowing them to take up glucose from your blood. This rapid action makes it different from regular human insulin, which takes 30 minutes to an hour to start working.

Who uses it

Doctors prescribe insulin lispro for people with type 1 diabetes and some people with type 2 diabetes who need mealtime insulin coverage. It's often used alongside a longer-acting insulin that works throughout the day.

Administration

Insulin lispro comes as an injectable medication. You inject it under the skin just before or during meals. Your doctor will show you how to inject it properly and help you figure out the right dose for your needs.

Side effects and considerations

Common side effects include low blood sugar (hypoglycemia), weight gain, and injection site reactions. Hypoglycemia can be serious, so it's important to carry fast-acting carbohydrates and know how to recognise the warning signs.

Cost and access

Insulin lispro is available as a generic medication and under brand names including Humalog and Lyumjev. Price varies significantly depending on your insurance coverage and whether you use a brand or generic version.

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