Lisdexamfetamine: What You Need to Know About This ADHD Medication

Lisdexamfetamine is a prescription stimulant used to treat ADHD and binge eating disorder. Learn how it works, what to expect, and what matters before you start.

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What is lisdexamfetamine?

Lisdexamfetamine is a prescription stimulant medication used to treat attention deficit hyperactivity disorder (ADHD) in children and adults, and binge eating disorder in adults. It's sold under the brand name Vyvanse.

How it works

Lisdexamfetamine is a prodrug, meaning your body converts it into its active form (dexamphetamine) after you take it. This delayed activation can reduce the potential for misuse compared to medications that work immediately.

Common uses

Your doctor may prescribe lisdexamfetamine for:

  • ADHD symptoms in people aged 6 and older
  • Binge eating disorder in adults

What to expect

Most people taking lisdexamfetamine notice improved focus and attention within 1 to 2 hours. Effects typically last 10 to 12 hours. Your doctor will start with a low dose and adjust based on your response and tolerance.

Side effects

Common side effects include decreased appetite, sleep problems, elevated heart rate, and anxiety. Serious side effects are rare but can include chest pain, severe headaches, or unusual changes in mood.

Before you start

Tell your doctor if you have a history of heart problems, high blood pressure, mental health conditions, or substance use. Lisdexamfetamine can interact with other medications, so provide a complete medication list.

Cost and access

Lisdexamfetamine is a controlled substance requiring a new prescription each month. Insurance coverage varies. Brand-name Vyvanse is expensive; generic lisdexamfetamine is less costly but may not be available everywhere.

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