Norethindrone: Uses, dosage and how it works

Norethindrone is a progestin used in birth control pills and hormone therapy. Learn about dosage, side effects and how it compares to other contraceptive options.

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What is norethindrone?

Norethindrone is a synthetic progestin, a hormone that mimics progesterone. It's used in birth control pills, combination contraceptives, and hormone replacement therapy.

How norethindrone works

Norethindrone prevents pregnancy by thickening cervical mucus to block sperm, thinning the uterine lining, and suppressing ovulation. In hormone therapy, it helps balance estrogen levels and manage menopausal symptoms.

Common uses

Doctors prescribe norethindrone for:

  • Hormonal contraception (birth control pills, often combined with ethinyl estradiol)
  • Heavy or irregular menstrual bleeding
  • Endometriosis
  • Hormone replacement therapy in menopause
  • Abnormal uterine bleeding

Dosage

Dosage depends on the specific medication and condition being treated. Birth control pills containing norethindrone typically contain 0.35 mg to 1 mg per pill. Always follow your prescriber's instructions.

Side effects

Common side effects include nausea, headaches, breast tenderness, and mood changes. Most side effects improve after a few months. Serious side effects are rare but can include blood clots, stroke, or heart attack, particularly in people who smoke or have other risk factors.

Getting norethindrone

Norethindrone is available by prescription only. You can obtain it through in-person visits with a gynecologist, primary care doctor, or via telehealth providers who offer birth control prescriptions online.

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