Progesterone: uses, side effects and how it works

Progesterone is a hormone that regulates the menstrual cycle and supports pregnancy. Learn how it works, what it treats, and what to expect from side effects.

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Progesterone is a hormone your body produces naturally. It plays a key role in regulating your menstrual cycle and preparing your body for pregnancy.

Doctors prescribe progesterone to treat several conditions. These include irregular periods, hormone replacement therapy during menopause, and to prevent miscarriage in people with a history of pregnancy loss. It can also be used to manage abnormal uterine bleeding.

Progesterone comes in multiple forms: oral tablets, injections, vaginal suppositories, and creams. Your doctor will choose the form and dose based on your specific condition and medical history.

Common side effects include drowsiness, headache, mood changes, and breast tenderness. Most side effects are mild and improve over time. More serious side effects are rare but can include blood clots and allergic reactions.

Progesterone works by mimicking the natural hormone your body makes after ovulation. This helps regulate your cycle, thicken the uterine lining to support pregnancy, and balance other hormones.

If you're considering progesterone, discuss with your doctor whether it's right for you. Be clear about your medical history, especially any history of blood clots, liver disease, or hormone-sensitive cancers.

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