Spironolactone: What It Treats and How It Works

Spironolactone is a potassium-sparing diuretic and aldosterone antagonist used to treat high blood pressure, heart failure, and hormonal acne. See how it works and what to expect.

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Spironolactone is a potassium-sparing diuretic that blocks aldosterone, a hormone that controls salt and water balance in your body. Unlike most diuretics, it doesn't flush out potassium, which is why doctors often prescribe it alongside other blood pressure medications.

What spironolactone treats

Spironolactone is used for:

  • High blood pressure
  • Heart failure
  • Hormonal acne, especially in people assigned female at birth
  • Polycystic ovary syndrome (PCOS)
  • Excessive hair growth caused by hormonal imbalances

How it works

Spironolactone reduces the amount of fluid your body retains by blocking aldosterone in the kidneys. This lowers blood volume and blood pressure. For acne and hair growth, it works by blocking androgens, male hormones that can trigger these conditions.

Side effects and considerations

Common side effects include dizziness, headache, and nausea. Because it's potassium-sparing, your doctor will monitor potassium levels with blood tests. High potassium can be dangerous. Avoid potassium supplements and high-potassium foods unless your doctor says otherwise.

Spironolactone can cause breast tenderness and irregular periods. It's not recommended during pregnancy.

Getting spironolactone online

You can get a spironolactone prescription through telehealth providers who offer dermatology or general practitioner consultations. Prices range widely depending on your insurance and pharmacy.

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